OPG/RANKL/RANK axis is a critical inflammatory signaling system in ischemic brain in mice

Osteoprotegerin (OPG) is a soluble secreted protein and a decoy receptor, which inhibits a receptor activator of nuclear factor κB (NF-κB) ligand (RANKL)/the receptor activator of NF-κB (RANK) signaling. Recent clinical studies have shown that a high-serum-OPG level is associated with unfavorable ou...

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Hlavní autoři: Shimamura, Munehisa, Nakagami, Hironori, Osako, Mariana K., Kurinami, Hitomi, Koriyama, Hiroshi, Zhengda, Pang, Tomioka, Hideki, Tenma, Akiko, Wakayama, Kouji, Morishita, Ryuichi
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2014
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4050556/
https://ncbi.nlm.nih.gov/pubmed/24847069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1400544111
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