Therapeutic vaccine against DPP4 improves glucose metabolism in mice

The increasing prevalence of type 2 diabetes mellitus is associated with a significant economic burden. We developed a dipeptidyl peptidase 4 (DPP4)-targeted immune therapy to increase glucagon-like peptide 1 hormone levels and improve insulin sensitivity for the prevention and treatment of type 2 d...

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Detalhes bibliográficos
Main Authors: Pang, Zhengda, Nakagami, Hironori, Osako, Mariana K., Koriyama, Hiroshi, Nakagami, Futoshi, Tomioka, Hideki, Shimamura, Munehisa, Kurinami, Hitomi, Takami, Yoichi, Morishita, Ryuichi, Rakugi, Hiromi
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3977240/
https://ncbi.nlm.nih.gov/pubmed/24639549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1322009111
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