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Mitochondrial control through nutritionally regulated global histone H3 lysine-4 demethylation

Histone demethylation by Jumonji-family proteins is coupled with the decarboxylation of α-ketoglutarate (αKG) to yield succinate, prompting hypotheses that their activities are responsive to levels of these metabolites in the cell. Consistent with this paradigm we show here that the Saccharomyces ce...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Rep
Prif Awduron: Soloveychik, Maria, Xu, Mengshu, Zaslaver, Olga, Lee, Kwanyin, Narula, Ashrut, Jiang, River, Rosebrock, Adam P., Caudy, Amy A., Meneghini, Marc D.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5126570/
https://ncbi.nlm.nih.gov/pubmed/27897198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep37942
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