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Mitochondrial control through nutritionally regulated global histone H3 lysine-4 demethylation
Histone demethylation by Jumonji-family proteins is coupled with the decarboxylation of α-ketoglutarate (αKG) to yield succinate, prompting hypotheses that their activities are responsive to levels of these metabolites in the cell. Consistent with this paradigm we show here that the Saccharomyces ce...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5126570/ https://ncbi.nlm.nih.gov/pubmed/27897198 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep37942 |
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