Foot-and-Mouth Disease Virus Viroporin 2B Antagonizes RIG-I-Mediated Antiviral Effects by Inhibition of Its Protein Expression

The role of retinoic acid-inducible gene I (RIG-I) in foot-and-mouth disease virus (FMDV)-infected cells remains unknown. Here, we showed that RIG-I inhibits FMDV replication in host cells. FMDV infection increased the transcription of RIG-I, while it decreased RIG-I protein expression. A detailed a...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Zhu, Zixiang, Wang, Guoqing, Yang, Fan, Cao, Weijun, Mao, Ruoqing, Du, Xiaoli, Zhang, Xiangle, Li, Chuntian, Li, Dan, Zhang, Keshan, Shu, Hongbing, Liu, Xiangtao, Zheng, Haixue
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5126369/
https://ncbi.nlm.nih.gov/pubmed/27707918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01310-16
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