Sulforaphane is a Nrf2-independent inhibitor of mitochondrial fission

The KEAP1-Nrf2-ARE antioxidant system is a principal means by which cells respond to oxidative and xenobiotic stresses. Sulforaphane (SFN), an electrophilic isothiocyanate derived from cruciferous vegetables, activates the KEAP1-Nrf2-ARE pathway and has become a molecule-of-interest in the treatment...

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Bibliographic Details
Published in:Redox Biol
Main Authors: O'Mealey, Gary B., Berry, William L., Plafker, Scott M.
Format: Artigo
Language:Inglês
Published: Elsevier 2016
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5126150/
https://ncbi.nlm.nih.gov/pubmed/27889639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2016.11.007
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