Planar cell polarity genes Celsr1 and Vangl2 are necessary for kidney growth, differentiation, and rostrocaudal patterning

The mammalian kidney contains nephrons comprising glomeruli and tubules joined to ureteric bud–derived collecting ducts. It has a characteristic bean-like shape, with near-complete rostrocaudal symmetry around the hilum. Here we show that Celsr1, a planar cell polarity (PCP) gene implicated in neura...

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Detalhes bibliográficos
Publicado no:Kidney Int
Main Authors: Brzóska, Hortensja Ł., d’Esposito, Angela M., Kolatsi-Joannou, Maria, Patel, Vishal, Igarashi, Peter, Lei, Yunping, Finnell, Richard H., Lythgoe, Mark F., Woolf, Adrian S., Papakrivopoulou, Eugenia, Long, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2016
Assuntos:
Basic Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5126096/
https://ncbi.nlm.nih.gov/pubmed/27597235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.kint.2016.07.011
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