Heterozygous Vangl2(Looptail) mice reveal novel roles for the planar cell polarity pathway in adult lung homeostasis and repair

Lung diseases impose a huge economic and health burden worldwide. A key aspect of several adult lung diseases, such as idiopathic pulmonary fibrosis (IPF) and chronic obstructive pulmonary disease (COPD), including emphysema, is aberrant tissue repair, which leads to an accumulation of damage and im...

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Udgivet i:Dis Model Mech
Main Authors: Poobalasingam, Thanushiyan, Yates, Laura L., Walker, Simone A., Pereira, Miguel, Gross, Nina Y., Ali, Akmol, Kolatsi-Joannou, Maria, Jarvelin, Marjo-Riitta, Pekkanen, Juha, Papakrivopoulou, Eugenia, Long, David A., Griffiths, Mark, Wagner, Darcy, Königshoff, Melanie, Hind, Matthew, Minelli, Cosetta, Lloyd, Clare M., Dean, Charlotte H.
Format: Artigo
Sprog:Inglês
Udgivet: The Company of Biologists Ltd 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5399569/
https://ncbi.nlm.nih.gov/pubmed/28237967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.028175
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