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Receptor activator of nuclear factor kappa-B (RANK) independent osteoclast formation and bone erosion in inflammatory arthritis
OBJECTIVE: Pro-inflammatory molecules promote osteoclast-mediated bone erosion by upregulating local RANKL production. However, recent evidence suggests that combinations of cytokines, such as TNFα plus IL-6, induce RANKL-independent osteoclastogenesis. This study sought to better understand TNFα/IL...
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| Publicado en: | Arthritis Rheumatol |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5125876/ https://ncbi.nlm.nih.gov/pubmed/27563728 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.39837 |
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