Receptor activator of nuclear factor kappa-B (RANK) independent osteoclast formation and bone erosion in inflammatory arthritis

OBJECTIVE: Pro-inflammatory molecules promote osteoclast-mediated bone erosion by upregulating local RANKL production. However, recent evidence suggests that combinations of cytokines, such as TNFα plus IL-6, induce RANKL-independent osteoclastogenesis. This study sought to better understand TNFα/IL...

詳細記述

保存先:
書誌詳細
出版年:Arthritis Rheumatol
主要な著者: O’Brien, William, Fissel, Brian M., Maeda, Yukiko, Yan, Jing, Ge, Xianpeng, Gravallese, Ellen M., Aliprantis, Antonios O., Charles, Julia F.
フォーマット: Artigo
言語:Inglês
出版事項: 2016
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5125876/
https://ncbi.nlm.nih.gov/pubmed/27563728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.39837
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