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Computational Discovery of Putative Leads for Drug Repositioning through Drug-Target Interaction Prediction

De novo experimental drug discovery is an expensive and time-consuming task. It requires the identification of drug-target interactions (DTIs) towards targets of biological interest, either to inhibit or enhance a specific molecular function. Dedicated computational models for protein simulation and...

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Vydáno v:PLoS Comput Biol
Hlavní autoři: Coelho, Edgar D., Arrais, Joel P., Oliveira, José Luís
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2016
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5125559/
https://ncbi.nlm.nih.gov/pubmed/27893735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005219
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