Large-scale Direct Targeting for Drug Repositioning and Discovery

A system-level identification of drug-target direct interactions is vital to drug repositioning and discovery. However, the biological means on a large scale remains challenging and expensive even nowadays. The available computational models mainly focus on predicting indirect interactions or direct...

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Vydáno v:Sci Rep
Hlavní autoři: Zheng, Chunli, Guo, Zihu, Huang, Chao, Wu, Ziyin, Li, Yan, Chen, Xuetong, Fu, Yingxue, Ru, Jinlong, Ali Shar, Piar, Wang, Yuan, Wang, Yonghua
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2015
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4496667/
https://ncbi.nlm.nih.gov/pubmed/26155766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep11970
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