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A constitutively active holoenzyme form of the cAMP-dependent protein kinase.

The major function of the regulatory (R) subunit of the cAMP-dependent protein kinase is to bind tightly to the catalytic (C) subunit to form an inactive holoenzyme in the absence of cAMP. The hinge region of the R subunit resembles the substrate recognition site for the C subunit and is known to be...

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Bibliografiska uppgifter
Huvudupphovsmän: Wang, Y H, Scott, J D, McKnight, G S, Krebs, E G
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1991
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC51249/
https://ncbi.nlm.nih.gov/pubmed/1848703
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