A constitutively active holoenzyme form of the cAMP-dependent protein kinase.
The major function of the regulatory (R) subunit of the cAMP-dependent protein kinase is to bind tightly to the catalytic (C) subunit to form an inactive holoenzyme in the absence of cAMP. The hinge region of the R subunit resembles the substrate recognition site for the C subunit and is known to be...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
1991
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC51249/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1848703/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.6.2446 |
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