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Identification of an inhibitory region of the heat-stable protein inhibitor of the cAMP-dependent protein kinase.

The present study was undertaken in order to identify the inhibitory site of the heat-stable inhibitor of cAMP-dependent protein kinase (PKI) and to synthesize a peptide that could serve as a useful inhibitor of the enzyme. Digestion of purified PKI by mast cell proteinase II yielded a peptide fragm...

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Detalhes bibliográficos
Main Authors: Scott, J D, Fischer, E H, Demaille, J G, Krebs, E G
Formato: Artigo
Idioma:Inglês
Publicado em: 1985
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC390417/
https://ncbi.nlm.nih.gov/pubmed/2989819
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