Targeted Inhibition of the miR-199a/214 Cluster by CRISPR Interference Augments the Tumor Tropism of Human Induced Pluripotent Stem Cell-Derived Neural Stem Cells under Hypoxic Condition

The human induced pluripotent stem cell (hiPSC) provides a breakthrough approach that helps overcoming ethical and allergenic challenges posed in application of neural stem cells (NSCs) in targeted cancer gene therapy. However, the tumor-tropic capacity of hiPSC-derived NSCs (hiPS-NSCs) still has mu...

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Detalhes bibliográficos
Publicado no:Stem Cells Int
Main Authors: Luo, Yumei, Xu, Xuehu, An, Xiuli, Sun, Xiaofang, Wang, Shu, Zhu, Detu
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5124688/
https://ncbi.nlm.nih.gov/pubmed/27965712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/3598542
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