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The role of phenotypic plasticity in the escape of cancer cells from targeted therapy

Targeted therapy has proven to be beneficial at producing significant responses in patients with a wide variety of cancers. Despite initially impressive responses, most individuals ultimately fail these therapies and show signs of drug resistance. Very few patients are ever cured. Emerging evidence...

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Detalles Bibliográficos
Publicado en:Biochem Pharmacol
Main Authors: Emmons, Micheal F., Faiao-Flores, Fernanda, Smalley, Keiran S.M.
Formato: Artigo
Idioma:Inglês
Publicado: 2016
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5124530/
https://ncbi.nlm.nih.gov/pubmed/27349985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2016.06.014
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