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The role of phenotypic plasticity in the escape of cancer cells from targeted therapy

Targeted therapy has proven to be beneficial at producing significant responses in patients with a wide variety of cancers. Despite initially impressive responses, most individuals ultimately fail these therapies and show signs of drug resistance. Very few patients are ever cured. Emerging evidence...

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Pubblicato in:Biochem Pharmacol
Autori principali: Emmons, Micheal F., Faiao-Flores, Fernanda, Smalley, Keiran S.M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5124530/
https://ncbi.nlm.nih.gov/pubmed/27349985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2016.06.014
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