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Managing leptomeningeal melanoma metastases in the era of immune and targeted therapy

Melanoma frequently metastasizes to the brain, with CNS involvement being clinically evident in ~30% of patients (as high as 75% at autopsy). In ~5% cases melanoma cells also metastasize to the leptomeninges, the sub-arachnoid space and cerebrospinal fluid (CSF). Patients with leptomeningeal melanom...

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Detalhes bibliográficos
Publicado no:Int J Cancer
Main Authors: Smalley, Keiran S.M., Fedorenko, Inna V., Kenchappa, Rajappa, Sahebjam, Solmaz, Forsyth, Peter A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4939138/
https://ncbi.nlm.nih.gov/pubmed/27084046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.30147
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