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SHH Ventralizes the Otocyst by Maintaining Basal PKA Activity and Regulating GLI3 Signaling

During development of the inner ear, secreted morphogens act coordinately to establish otocyst dorsoventral polarity. Among these, Sonic hedgehog (SHH) plays a critical role in determining ventral polarity. However, how this extracellular signal is transduced intracellularly to establish ventral pol...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Dev Biol
Päätekijät: Ohta, Sho, Wang, Baolin, Mansour, Suzanne L., Schoenwolf, Gary C.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5124394/
https://ncbi.nlm.nih.gov/pubmed/27720745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2016.10.004
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