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SHH Ventralizes the Otocyst by Maintaining Basal PKA Activity and Regulating GLI3 Signaling
During development of the inner ear, secreted morphogens act coordinately to establish otocyst dorsoventral polarity. Among these, Sonic hedgehog (SHH) plays a critical role in determining ventral polarity. However, how this extracellular signal is transduced intracellularly to establish ventral pol...
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| Publicado no: | Dev Biol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5124394/ https://ncbi.nlm.nih.gov/pubmed/27720745 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2016.10.004 |
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