Noninvasive detection of enzyme activity in tumor models of human ovarian cancer using catalyCEST MRI

PURPOSE: We proposed to detect the in vivo enzyme activity of γ-glutamyl transferase (GGT) within mouse models of human ovarian cancers using catalyCEST MRI with a diamagnetic CEST agent. METHODS: A CEST-FISP MRI protocol and a diamagnetic CEST agent were developed to detect GGT enzyme activity in b...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Magn Reson Med
Päätekijät: Sinharay, Sanhita, Randtke, Edward A., Jones, Kyle M., Howison, Christine M., Chambers, Setsuko K., Kobayashi, Hisataka, Pagel, Mark D.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2016
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5123981/
https://ncbi.nlm.nih.gov/pubmed/27221386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mrm.26278
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