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Neurotrophin signaling is required for glucose-induced insulin secretion
Insulin secretion by pancreatic islet β-cells is critical for glucose homeostasis, and a blunted β-cell secretory response is an early deficit in type 2 diabetes. Here, we uncover a regulatory mechanism by which glucose recruits vascular-derived neurotrophins to control insulin secretion. Nerve Grow...
Shranjeno v:
| izdano v: | Dev Cell |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2016
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5123838/ https://ncbi.nlm.nih.gov/pubmed/27825441 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2016.10.003 |
| Oznake: |
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