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Sympathetic innervation during development is necessary for pancreatic islet architecture and functional maturation

Sympathetic neurons depend on target-derived neurotrophic cues to control their survival and growth. However, whether sympathetic innervation contributes reciprocally to the development of target tissues is less clear. Here, we report that sympathetic innervation is necessary for the formation of th...

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Autori principali: Borden, Philip, Houtz, Jessica, Leach, Steven D., Kuruvilla, Rejji
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3740126/
https://ncbi.nlm.nih.gov/pubmed/23850289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2013.06.019
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