Lipids reprogram metabolism to become a major carbon source for histone acetylation

Cells integrate nutrient sensing and metabolism to coordinate proper cellular responses to a particular nutrient source. For example, glucose drives a gene expression program characterized by activating genes involved in its metabolism, in part, by increasing glucose-derived histone acetylation. Her...

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Veröffentlicht in:Cell Rep
Hauptverfasser: McDonnell, Eoin, Crown, Scott B., Fox, Douglas B., Kitir, Betül, Ilkayeva, Olga R., Olsen, Christian A., Grimsrud, Paul A., Hirschey, Matthew D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5123807/
https://ncbi.nlm.nih.gov/pubmed/27806287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.10.012
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