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Glucose Metabolism as a Target of Histone Deacetylase Inhibitors

The therapeutic efficacy of histone deacetylase inhibitors (HDACI) is generally attributed to their ability to alter gene expression secondary to their effects on the acetylation status of transcription factors and histones. However, because HDACIs exhibit similar transcriptional effects in most cel...

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Detalhes bibliográficos
Main Authors: Wardell, Suzanne E., Ilkayeva, Olga R., Wieman, Heather L., Frigo, Daniel E., Rathmell, Jeffrey C., Newgard, Christopher B., McDonnell, Donald P.
Formato: Artigo
Idioma:Inglês
Publicado em: The Endocrine Society 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2654518/
https://ncbi.nlm.nih.gov/pubmed/19106193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2008-0179
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