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Glucose Metabolism as a Target of Histone Deacetylase Inhibitors

The therapeutic efficacy of histone deacetylase inhibitors (HDACI) is generally attributed to their ability to alter gene expression secondary to their effects on the acetylation status of transcription factors and histones. However, because HDACIs exhibit similar transcriptional effects in most cel...

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Autors principals: Wardell, Suzanne E., Ilkayeva, Olga R., Wieman, Heather L., Frigo, Daniel E., Rathmell, Jeffrey C., Newgard, Christopher B., McDonnell, Donald P.
Format: Artigo
Idioma:Inglês
Publicat: The Endocrine Society 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2654518/
https://ncbi.nlm.nih.gov/pubmed/19106193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2008-0179
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