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Base-resolution profiling of active DNA demethylation using methylase-assisted bisulfite sequencing (MAB-seq) and caMAB-seq
A complete understanding of the function of Ten-eleven translocation (TET) family of dioxygenase-mediated DNA demethylation requires new methods to quantitatively map oxidized 5-methylcytosine (5mC) bases at high-resolution. We have recently developed a methylase-assisted bisulfite sequencing (MAB-s...
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| Veröffentlicht in: | Nat Protoc |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5123565/ https://ncbi.nlm.nih.gov/pubmed/27172168 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nprot.2016.069 |
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