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Single-base resolution analysis of active DNA demethylation using methylase-assisted bisulfite sequencing
Active DNA demethylation in mammals involves TET-mediated iterative oxidation of 5-methylcytosine (5mC)/5-hydroxymethylcytosine (5hmC) and subsequent excision repair of highly oxidized cytosine bases 5-formylcytosine (5fC)/5-carboxylcytosine (5caC) by Thymine DNA glycosylase (TDG). However, quantita...
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| Publicado no: | Nat Biotechnol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4269366/ https://ncbi.nlm.nih.gov/pubmed/25362244 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.3073 |
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