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Base-resolution profiling of active DNA demethylation using methylase-assisted bisulfite sequencing (MAB-seq) and caMAB-seq

A complete understanding of the function of Ten-eleven translocation (TET) family of dioxygenase-mediated DNA demethylation requires new methods to quantitatively map oxidized 5-methylcytosine (5mC) bases at high-resolution. We have recently developed a methylase-assisted bisulfite sequencing (MAB-s...

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Detalhes bibliográficos
Publicado no:Nat Protoc
Main Authors: Wu, Hao, Wu, Xiaoji, Zhang, Yi
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5123565/
https://ncbi.nlm.nih.gov/pubmed/27172168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nprot.2016.069
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