Safety of intrathecal autologous adipose-derived mesenchymal stromal cells in patients with ALS

OBJECTIVE: To determine the safety of intrathecal autologous adipose-derived mesenchymal stromal cell treatment for amyotrophic lateral sclerosis (ALS). METHODS: Participants with ALS were enrolled and treated in this phase I dose-escalation safety trial, ranging from 1 × 10(7) (single dose) to 1 ×...

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Udgivet i:Neurology
Main Authors: Staff, Nathan P., Madigan, Nicolas N., Morris, Jonathan, Jentoft, Mark, Sorenson, Eric J., Butler, Greg, Gastineau, Dennis, Dietz, Allan, Windebank, Anthony J.
Format: Artigo
Sprog:Inglês
Udgivet: Lippincott Williams & Wilkins 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5123559/
https://ncbi.nlm.nih.gov/pubmed/27784774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000003359
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