Intrathecal administration of autologous mesenchymal stem cells in multiple system atrophy

OBJECTIVE: This phase I/II study sought to explore intrathecal administration of mesenchymal stem cells (MSCs) as therapeutic approach to multiple system atrophy (MSA). METHODS: Utilizing a dose-escalation design, we delivered between 10 and 200 million adipose-derived autologous MSCs intrathecally...

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Опубликовано в: :Neurology
Главные авторы: Singer, Wolfgang, Dietz, Allan B., Zeller, Anita D., Gehrking, Tonette L., Schmelzer, James D., Schmeichel, Ann M., Gehrking, Jade A., Suarez, Mariana D., Sletten, David M., Minota Pacheco, Karla V., Coon, Elizabeth A., Sandroni, Paola, Benarroch, Eduardo E., Fealey, Robert D., Matsumoto, Joseph Y., Bower, James H., Hassan, Anhar, McKeon, Andrew, Windebank, Anthony J., Mandrekar, Jay N., Low, Phillip A.
Формат: Artigo
Язык:Inglês
Опубликовано: Lippincott Williams & Wilkins 2019
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6659003/
https://ncbi.nlm.nih.gov/pubmed/31152011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000007720
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