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A Safety Study on Intrathecal Delivery of Autologous Mesenchymal Stromal Cells in Rabbits Directly Supporting Phase I Human Trials

BACKGROUND: There are no effective treatments that slow the progression of neurodegenerative diseases. A major challenge of treatment in neurodegenerative diseases is appropriate delivery of pharmaceuticals into the cerebrospinal fluid (CSF) of affected individuals. Mesenchymal stromal cells (MSCs –...

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Detalhes bibliográficos
Publicado no:Transfusion
Main Authors: Chen, Bingkun K., Staff, Nathan P., Knight, Andrew M., Nesbitt, Jarred J., Butler, Greg W., Padley, Douglas J., Parisi, Joseph E., Dietz, Allan B., Windebank, Anthony J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4428970/
https://ncbi.nlm.nih.gov/pubmed/25413276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/trf.12938
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