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KAOS: a new automated computational method for the identification of overexpressed genes

BACKGROUND: Kinase over-expression and activation as a consequence of gene amplification or gene fusion events is a well-known mechanism of tumorigenesis. The search for novel rearrangements of kinases or other druggable genes may contribute to understanding the biology of cancerogenesis, as well as...

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Publicat a:BMC Bioinformatics
Autors principals: Nuzzo, Angelo, Carapezza, Giovanni, Di Bella, Sebastiano, Pulvirenti, Alfredo, Isacchi, Antonella, Bosotti, Roberta
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5123341/
https://ncbi.nlm.nih.gov/pubmed/28185541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-016-1188-1
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