KAOS: a new automated computational method for the identification of overexpressed genes

BACKGROUND: Kinase over-expression and activation as a consequence of gene amplification or gene fusion events is a well-known mechanism of tumorigenesis. The search for novel rearrangements of kinases or other druggable genes may contribute to understanding the biology of cancerogenesis, as well as...

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Vydáno v:BMC Bioinformatics
Hlavní autoři: Nuzzo, Angelo, Carapezza, Giovanni, Di Bella, Sebastiano, Pulvirenti, Alfredo, Isacchi, Antonella, Bosotti, Roberta
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2016
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5123341/
https://ncbi.nlm.nih.gov/pubmed/28185541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-016-1188-1
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