ISGylation controls exosome secretion by promoting lysosomal degradation of MVB proteins

Exosomes are vesicles secreted to the extracellular environment through fusion with the plasma membrane of specific endosomes called multivesicular bodies (MVB) and mediate cell-to-cell communication in many biological processes. Posttranslational modifications are involved in the sorting of specifi...

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Bibliografiska uppgifter
I publikationen:Nat Commun
Huvudupphovsmän: Villarroya-Beltri, Carolina, Baixauli, Francesc, Mittelbrunn, María, Fernández-Delgado, Irene, Torralba, Daniel, Moreno-Gonzalo, Olga, Baldanta, Sara, Enrich, Carlos, Guerra, Susana, Sánchez-Madrid, Francisco
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2016
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5123068/
https://ncbi.nlm.nih.gov/pubmed/27882925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13588
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