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ISGylation controls exosome secretion by promoting lysosomal degradation of MVB proteins

Exosomes are vesicles secreted to the extracellular environment through fusion with the plasma membrane of specific endosomes called multivesicular bodies (MVB) and mediate cell-to-cell communication in many biological processes. Posttranslational modifications are involved in the sorting of specifi...

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Библиографические подробности
Опубликовано в: :Nat Commun
Главные авторы: Villarroya-Beltri, Carolina, Baixauli, Francesc, Mittelbrunn, María, Fernández-Delgado, Irene, Torralba, Daniel, Moreno-Gonzalo, Olga, Baldanta, Sara, Enrich, Carlos, Guerra, Susana, Sánchez-Madrid, Francisco
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2016
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5123068/
https://ncbi.nlm.nih.gov/pubmed/27882925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13588
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