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ISGylation controls exosome secretion by promoting lysosomal degradation of MVB proteins
Exosomes are vesicles secreted to the extracellular environment through fusion with the plasma membrane of specific endosomes called multivesicular bodies (MVB) and mediate cell-to-cell communication in many biological processes. Posttranslational modifications are involved in the sorting of specifi...
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| Publicado no: | Nat Commun |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5123068/ https://ncbi.nlm.nih.gov/pubmed/27882925 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13588 |
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