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Epigenetic mechanisms drive the progression of neurofibromas to malignant peripheral nerve sheath tumors
THINKING OUTSIDE THE BOX: The polycomb repressive complex 2 (PRC2) is a histone methyltransferase complex known to repress gene expression. There is a large body of experimental evidence that supports its role in promoting tumorigenicity by suppressing tumor suppressor genes. Here, we discuss the su...
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| 發表在: | Surg Neurol Int |
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| Main Authors: | , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Medknow Publications & Media Pvt Ltd
2016
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5122817/ https://ncbi.nlm.nih.gov/pubmed/27920939 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/2152-7806.194058 |
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