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Epigenetic mechanisms drive the progression of neurofibromas to malignant peripheral nerve sheath tumors
THINKING OUTSIDE THE BOX: The polycomb repressive complex 2 (PRC2) is a histone methyltransferase complex known to repress gene expression. There is a large body of experimental evidence that supports its role in promoting tumorigenicity by suppressing tumor suppressor genes. Here, we discuss the su...
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| Pubblicato in: | Surg Neurol Int |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Medknow Publications & Media Pvt Ltd
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5122817/ https://ncbi.nlm.nih.gov/pubmed/27920939 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/2152-7806.194058 |
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