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Regulation of Cytochrome P450 2B10 (CYP2B10) Expression in Liver by Peroxisome Proliferator-activated Receptor-β/δ Modulation of SP1 Promoter Occupancy

Alcoholic liver disease is a pathological condition caused by overconsumption of alcohol. Because of the high morbidity and mortality associated with this disease, there remains a need to elucidate the molecular mechanisms underlying its etiology and to develop new treatments. Because peroxisome pro...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Koga, Takayuki, Yao, Pei-Li, Goudarzi, Maryam, Murray, Iain A., Balandaram, Gayathri, Gonzalez, Frank J., Perdew, Gary H., Fornace, Albert J., Peters, Jeffrey M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5122791/
https://ncbi.nlm.nih.gov/pubmed/27765815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.755447
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