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Four-and-a-half LIM Domains 1 (FHL1) Protein Interacts with the Rho Guanine Nucleotide Exchange Factor PLEKHG2/FLJ00018 and Regulates Cell Morphogenesis

PLEKHG2/FLJ00018 is a Gβγ-dependent guanine nucleotide exchange factor for the small GTPases Rac and Cdc42 and has been shown to mediate the signaling pathways leading to actin cytoskeleton reorganization. Here we showed that the zinc finger domain-containing protein four-and-a-half LIM domains 1 (F...

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Détails bibliographiques
Publié dans:J Biol Chem
Auteurs principaux: Sato, Katsuya, Kimura, Masashi, Sugiyama, Kazue, Nishikawa, Masashi, Okano, Yukio, Nagaoka, Hitoshi, Nagase, Takahiro, Kitade, Yukio, Ueda, Hiroshi
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5122788/
https://ncbi.nlm.nih.gov/pubmed/27765816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.759571
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