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Specific activation of PLEKHG2-induced serum response element-dependent gene transcription by four-and-a-half LIM domains (FHL) 1, but not FHL2 or FHL3

PLEKHG2 is a Gβγ- and Gαs-dependent guanine nucleotide exchange factor for Rac1 and Cdc42 small GTPases and has been shown to mediate signaling pathways such as those for actin cytoskeletal reorganization and serum response element (SRE)-dependent gene transcription. We have shown that the four-and-...

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Détails bibliographiques
Publié dans:Small GTPases
Auteurs principaux: Nishikawa, Masashi, Sato, Katsuya, Nakano, Shun, Yamakawa, Hisashi, Nagase, Takahiro, Ueda, Hiroshi
Format: Artigo
Langue:Inglês
Publié: Taylor & Francis 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6748362/
https://ncbi.nlm.nih.gov/pubmed/28489964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21541248.2017.1327838
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