The C-terminal Domains of Apoptotic BH3-only Proteins Mediate Their Insertion into Distinct Biological Membranes

Changes in the equilibrium of pro- and anti-apoptotic members of the B-cell lymphoma-2 (Bcl-2) protein family in the mitochondrial outer membrane (MOM) induce structural changes that commit cells to apoptosis. Bcl-2 homology-3 (BH3)-only proteins participate in this process by either activating pro-...

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Veröffentlicht in:J Biol Chem
Hauptverfasser: Andreu-Fernández, Vicente, García-Murria, María J., Bañó-Polo, Manuel, Martin, Juliette, Monticelli, Luca, Orzáez, Mar, Mingarro, Ismael
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2016
Schlagworte:
Membrane Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5122786/
https://ncbi.nlm.nih.gov/pubmed/27758854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.733634
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