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Polar/Ionizable Residues in Transmembrane Segments: Effects on Helix-Helix Packing
The vast majority of membrane proteins are anchored to biological membranes through hydrophobic α-helices. Sequence analysis of high-resolution membrane protein structures show that ionizable amino acid residues are present in transmembrane (TM) helices, often with a functional and/or structural rol...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3440369/ https://ncbi.nlm.nih.gov/pubmed/22984481 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0044263 |
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