Polar/Ionizable Residues in Transmembrane Segments: Effects on Helix-Helix Packing

The vast majority of membrane proteins are anchored to biological membranes through hydrophobic α-helices. Sequence analysis of high-resolution membrane protein structures show that ionizable amino acid residues are present in transmembrane (TM) helices, often with a functional and/or structural rol...

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Détails bibliographiques
Auteurs principaux: Bañó-Polo, Manuel, Baeza-Delgado, Carlos, Orzáez, Mar, Marti-Renom, Marc A., Abad, Concepción, Mingarro, Ismael
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2012
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3440369/
https://ncbi.nlm.nih.gov/pubmed/22984481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0044263
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