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The c-fms gene complements the mitogenic defect in mast cells derived from mutant W mice but not mi (microphthalmia) mice.

Mutations at three loci in the mouse--W, Steel Sl), and microphthalmia (mi)--can lead to a deficiency in melanocytes and mast cells. As well, W and Sl mutants can be anemic and sterile, whereas mi mice are osteopetrotic due to a monocyte/macrophage defect. Recent data have shown that the c-kit recep...

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Bibliografiske detaljer
Main Authors: Dubreuil, P, Forrester, L, Rottapel, R, Reedijk, M, Fujita, J, Bernstein, A
Format: Artigo
Sprog:Inglês
Udgivet: 1991
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC51227/
https://ncbi.nlm.nih.gov/pubmed/1826051
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