The c-fms gene complements the mitogenic defect in mast cells derived from mutant W mice but not mi (microphthalmia) mice.

Mutations at three loci in the mouse--W, Steel Sl), and microphthalmia (mi)--can lead to a deficiency in melanocytes and mast cells. As well, W and Sl mutants can be anemic and sterile, whereas mi mice are osteopetrotic due to a monocyte/macrophage defect. Recent data have shown that the c-kit recep...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Dubreuil, P, Forrester, L, Rottapel, R, Reedijk, M, Fujita, J, Bernstein, A
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1991
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC51227/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1826051/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.6.2341
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