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T-bet promotes the accumulation of encephalitogenic Th17 cells in the CNS
T-bet enhances the encephalitogenicity of myelin-reactive CD4(+) T cells, however its mechanism of action is unknown. In this study we show that T-bet confers a competitive advantage for the accumulation of IL-23 conditioned Th17 effector cells in the central nervous system (CNS). Impaired migration...
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| Publicado no: | J Neuroimmunol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5122469/ https://ncbi.nlm.nih.gov/pubmed/27242075 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneuroim.2016.05.007 |
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