Epidermal Growth Factor Receptor Silencing Blunts the Slow Force Response to Myocardial Stretch

BACKGROUND: Myocardial stretch increases force biphasically: the Frank‐Starling mechanism followed by the slow force response (SFR). Based on pharmacological strategies, we proposed that epidermal growth factor (EGF) receptor (EGFR or ErbB1) activation is crucial for SFR development. Pharmacological...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:J Am Heart Assoc
Auteurs principaux: Brea, María S., Díaz, Romina G., Escudero, Daiana S., Caldiz, Claudia I., Portiansky, Enrique L., Morgan, Patricio E., Pérez, Néstor G.
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2016
Sujets:
Original Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5121502/
https://ncbi.nlm.nih.gov/pubmed/27744404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.116.004017
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires