Epidermal Growth Factor Receptor Silencing Blunts the Slow Force Response to Myocardial Stretch

BACKGROUND: Myocardial stretch increases force biphasically: the Frank‐Starling mechanism followed by the slow force response (SFR). Based on pharmacological strategies, we proposed that epidermal growth factor (EGF) receptor (EGFR or ErbB1) activation is crucial for SFR development. Pharmacological...

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Detaylı Bibliyografya
Yayımlandı:J Am Heart Assoc
Asıl Yazarlar: Brea, María S., Díaz, Romina G., Escudero, Daiana S., Caldiz, Claudia I., Portiansky, Enrique L., Morgan, Patricio E., Pérez, Néstor G.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2016
Konular:
Original Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5121502/
https://ncbi.nlm.nih.gov/pubmed/27744404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.116.004017
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