Epidermal Growth Factor Receptor Silencing Blunts the Slow Force Response to Myocardial Stretch

BACKGROUND: Myocardial stretch increases force biphasically: the Frank‐Starling mechanism followed by the slow force response (SFR). Based on pharmacological strategies, we proposed that epidermal growth factor (EGF) receptor (EGFR or ErbB1) activation is crucial for SFR development. Pharmacological...

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Detalles Bibliográficos
Publicado en:J Am Heart Assoc
Main Authors: Brea, María S., Díaz, Romina G., Escudero, Daiana S., Caldiz, Claudia I., Portiansky, Enrique L., Morgan, Patricio E., Pérez, Néstor G.
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2016
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Original Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5121502/
https://ncbi.nlm.nih.gov/pubmed/27744404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.116.004017
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