Effect of Roux-en-Y Gastric Bypass on the NLRP3 Inflammasome in Pancreatic Islets from Zucker Diabetic Fatty Rats

PURPOSE: Diabetes and obesity are associated with inflammasome-mediated low-grade, chronic inflammation that may induce pancreatic beta-cell dysfunction and apoptosis. We examined the effects of Roux-en-Y gastric bypass (RYGB) surgery on NOD-like receptor family, pyrin domain containing-3 (NLRP3) in...

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Detalhes bibliográficos
Publicado no:Obes Surg
Main Authors: Mocanu, Andreea Oana, Mulya, Anny, Huang, Hazel, Dan, Olivia, Schauer, Philip R., Dinischiotu, Anca, Brethauer, Stacy A., Kirwan, John P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5121054/
https://ncbi.nlm.nih.gov/pubmed/27654903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11695-016-2373-z
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